Presentation

Presentation

This 2-week summer school will focus on enzyme, molecular biology and microbial engineering.

Date : June, 4^th -15^th, 2018

The summer school takes place on INSA Campus in Toulouse.

The course combines grounding in the field of life sciences (molecular biology, biochemistry, enzymology and microbiology) and in engineering sciences (biochemical engineering).

Objectives

The objectives of the proposed courses deal with the understanding of the most modern concepts in molecular biology as well as mastering the concepts of biocatalysis (enzymatic and microbial) for industrial developments.

Admission

Access condition

This program is dedicated to students having a M1 or M2 degree.

Deadline registration : March 18th, 2018

Application must be made directly to the organizing institution. No application is possible through this website. Please click on the link "See the course website" to find out how to apply.

Program

Training content

• Course 1 - Enzyme kinetics (3-4 hours)

The objectives are to give basic knowledge concerning the measurement of the enzymatic reaction rate and the associated mechanisms, and to establish the rate equations of complex enzymatic reactions.
(Enzyme classification, reaction mechanism, initial reaction rate/enzymatic activity, Michaelis-Menten equation, Inhibition/activation, Effect of temperature and pH, Allosteric enzymes)

• Course 2. Gene expression regulation (4-6 hours)

The aim of this course is to provide the molecular biology and gene regulation knowledge that is required to master biotechnology tools for optimizing and/or modifying microorganism of industrial interest.               

At the end of this course, the student will have understood and be able to explain (main concepts): (1) nucleic acids properties, genome organization and DNA replication and (2) gene transcription, RNA processing and messenger RNA translation leading from DNA to proteins. Proteins folding and modifications will also be briefly described and key elements of gene expression regulation will also be given. Thus, the student will be able to define and describe the main molecular elements allowing genome organization and gene expression.

• Course 3. Biochemical and Microbial Engineering (4-6h courses / 6-8h labworks / 2h tutorials)

Metabolism of industrial microbes, microbial kinetics and biochemical engineering.